| | Organization Name(s) | Located In |
| | S.M.A.C. | Markham |
 | S.W.I.F.T., Swift Self Help Support Groups, SWIFT, Strength to Walk in Freedom Together | Toronto (City of) |
| SAC Summer Camps | Aurora |
| Sacred Heart Church | King City |
| Safe Haven, Aurora House | Aurora |
| Safehaven Project for Community Living | Aurora |
| Saint Agnes Kouying Tsao Catholic Church | Markham |
| Saint Elizabeth Health Care | Markham |
| | Saint Elizabeth Health Care, Driver Assessment and Training Services | Toronto |
| Salvation Army | Toronto |
| Salvation Army, Richmond Hill Community Church | Richmond Hill |
| Salvation Army, Richmond Hill Thrift Store | Richmond Hill |
| Salvation Army, Sutton Youth Shelter | Sutton |
| Salvation Army Community and Family Services | Markham |
| Salvation Army Summer Camp | Newmarket |
| Salvation Army Thrift Store | Markham |
| Sanatan Mandir Cultural Centre | Markham |
| | Sandgate Women's Shelter | Sutton |
| | Santa Fest | Maple |
| Savaria Elevators Lifts Stairlifts Van Conversions | Greater Toronto Area |
| Save the Oak Ridges Moraine Coalition | Aurora |
| | SayItCornell.com | Markham |
| Scanlon Creek Centre for Education | Bradford West Gwillimbury |
| Scarborough Hospital, General Division | Scarborough |
| Scarborough Hospital (The), Birchmount Campus | Scarborough |
| Schizophrenia Society of Canada | Markham |
| Schizophrenia Society of Ontario | Toronto |
| Schizophrenia Society of Ontario, Toronto Chapter | Toronto |
| Scholars Education Centre, Tutors | Richmond Hill |
| Schomberg Agricultural Society | Schomberg |
| Schomberg Community and Agricultural Arena | Schomberg |
| | Schomberg Happy Times Seniors Club | Schomberg |
| Schomberg Horticultural Society | Schomberg |
| | Schomberg Lions Club | Schomberg |
| Schomberg Lions Club, Non-Profit Housing Corporation, Kitchen Breedon Manor | Schomberg |
| Schomberg Skating Club | Schomberg |
| | Schomberg Village Association, A Main Street Christmas | Schomberg |
| Schomberg/Dunkerron United Churches | Schomberg |
| Scott Mission | Toronto |
| Scouts Canada, 1st Stouffville Scouts | Stouffville |
| | Scouts Canada, Shining Waters Council, York Headwaters Area | Markham |
| Scouts Canada, York Headwaters | Toronto |
| Seaton Hiking Trail | Markham |
| Second Harvest | Toronto |
| Self-Help Ontario | Greater Toronto Area |
| Seneca College, Centre for Entrepreneurship | Markham |
| Seneca College, King Campus | King City |
| Seneca College, Work on Track, York Region Program | Markham |
| Seneca College, Workforce Skills Centre | Newmarket |
| Seneca College Employment and Community Services, Job Connect, Summer Jobs Service, Academic Upgrading | Markham |
| Seneca College of Applied Arts and Technology, King Observation Lab Teaching School - KOLTS, King Campus Child Care | King City |
| Seneca College of Applied Arts and Technology, Markham Campus | Markham |
| Seneca College of Applied Arts and Technology, Markham Campus, Employment Assistance Services | Markham |
| Seneca College of Applied Arts and Technology, Newnham Campus | Toronto |
| Seneca College Underwater Skills Course | King City |
| Seneca College Workforce Skills Centre Vaughan | Vaughan |
| Senior Tours Canada, Trips for Seniors | Toronto |
| Senior Wish Association | Aurora |
| | Seniors Christmas Light Tours | Markham |
| Seniors for Seniors | York Region |
| | Seniors Safety Symposiums, Bringing an Awareness of Senior Safety Issues to the Community, Seniors' Safety Calendar | Toronto |
| Service Canada | Markham |
| Service Canada, Employment Insurance Compassionate Care Benefits | Newmarket |
| Service Canada, Human Resources Development, Newmarket Satellite Office | Newmarket |
| | Service Canada, Job Bank | Canada |
| Service Ontario, Aurora | Aurora |
| Service Ontario, Central Production and Verification Services Branch | Toronto |
| Service Ontario, Registrar General Branch | Thunder Bay |
| | Service Ontario, Thunder Bay Production and Verification Services, Birth, Marriage and Death Certificate on line application | Thunder Bay District |
| Settlement and Education Partnership In York Region | Thornhill |
| Shaar Shalom Synagogue | Thornhill |
| Shadow Lake Centre | Stouffville |
| Shadowpath Theatre Productions | Richmond Hill |
| Sharon Temple | Sharon |
| Shaw Festival | Niagara-on-the-Lake |
| | Shelternet - Centre for Social Innovation | Toronto |
| Shepherd Village | Scarborough |
| Sheppard's Bush Trail | Aurora |
| Sheraton Parkway, Toronto North, Hotel, Suites and Conference Centre | Richmond Hill |
| | Sherwood Amberglen Ratepayers Association | Markham |
| Sherwood Court Long Term Care Centre | Maple |
| Shining Light Montessori School | Vaughan |
| Shining Through Centre for Children With Autism | Vaughan |
| Shining Through Centre for Children With Autism, Vaughan Campus | Vaughan |
| Shoppers Drug Mart | Richmond Hill |
| Shoppers Drug Mart | Richmond Hill |
| Shoppers Drug Mart | Richmond Hill |
| Shoppers Drug Mart | Markham |
| Shoppers Home Health Care | Markham |
| Shouldice Hospital | Thornhill |
| Silent Voice Canada | Toronto |
| Silver City, Famous Players | Richmond Hill |
| Silver Knights, Basketball | Richmond Hill |
| | Silver Knights Basketball Club | Markham |
| Single Horizons | Markham |
| SKILLS FOR CHANGE, Enhanced Language Training for Professionals | Toronto |
| Skyriders Trampoline Place | Richmond Hill |
| Sledge Hockey for the Physically Disabled | Thornhill |
| Slovak Canadian National Council | Richmond Hill |
| | Small Investor Protection Association | Markham |
| Smart Commute Central York | Newmarket |
| Smooth Transitions York Region | Aurora |
| SNAP Markham | Markham |
| | Social 60's | Markham |
| Social Benefits Tribunal | Toronto |
| Social Enterprise for Canada | Newmarket |
| Social Enterprise for Canada, Accreditation Assistance Access Centre | Vaughan |
| Social Enterprise for Canada, Bridge Translations | Newmarket |
| Social Enterprise for Canada, Our Lady of Grace Before and After School Program | Aurora |
| Social Services Network of York Region | Markham |
| | Social Worker Action Team | Mississauga |
| Society for the Preservation of Historic Thornhill | Thornhill |
| Society of St Vincent de Paul, Our Lady of Grace Conference | Aurora |
| Society of St Vincent de Paul, Our Lady Queen of the World | Richmond Hill |
| Society of St Vincent de Paul, St. Mary Immaculate Catholic Church Conference | Richmond Hill |
| | Society of the Community of Old Richmond Hill, SCORH, Ratepayer Group of Old Richmond Hill | Richmond Hill |
| | Society of York Region Artists | York Region |
| Solutions Family Counselling | Schomberg |
| Song Circle | Aurora |
| | SOS Children's Villages | Stouffville |
| | Soul to Sole | York Region |
| South Asian Family Support Services | Toronto |
| South Simcoe Community Information Centre ('CONTACT') | Alliston |
| | South Simcoe Railway | Tottenham |
| South Unionville Community Association | Markham |
| Southdown Institute (The) | Aurora |
| Southlake Regional Health Centre | Newmarket |
| Southlake Regional Health Centre, Child and Adolescent Mental Health, Child and Adolescent Crisis Program, Child and Family Clinic, Child and Adolescent Inpatient Unit | Newmarket |
| Southlake Regional Health Centre, Eating Disorders Program | Newmarket |
| Special Olympics Ontario | Toronto |
| Spina Bifida & Hydrocephalus Associations of Ontario | Ontario |
| Spirit of life | Markham |
| Sport Alliance Ontario | Toronto |
| Sport Aurora | Aurora |
| Sport Fencing Markham | Markham |
| | Sport Stacking Canada | Markham |
| Sportball, Sports Instruction for Kids | Toronto |
| Sports Village (The), Adult Winter Hockey | Vaughan |
| Springbrook Gardens | Richmond Hill |
| Springvale Baptist Church | Stouffville |
| St John Bosco Child Care Centre | Woodbridge |
| St Marks Child Care Centre | Woodbridge |
| St Peters Seniors Residence Woodbridge Incorporated | Woodbridge |
| St Andrews Presbyterian Church | Maple |
| St Andrews Presbyterian Church | Aurora |
| St Andrew's Presbyterian Church | Markham |
| St Andrew's Presbyterian Church, Martha's Table | Aurora |
| St Andrew's Scottish Country Dancing | Aurora |
| St Andrew's United Church | Markham |
| St Bishoy Coptic Orthodox Church | Stouffville |
| St Clare Child Care Centre | Woodbridge |
| St Clare of Assisi | Woodbridge |
| St Dimitrija Solunski Macedonian Orthodox Church | Markham |
| St George Antiochian Orthodox Church | Richmond Hill |
| St James Presbyterian Church | Stouffville |
| St John Ambulance York Region Branch | Richmond Hill |
| St Johns Anglican Church | Richmond Hill |
| St Joseph the Worker Catholic Parish | Thornhill |
| St Justin Martyr Church | Unionville |
| St Lawrence Centre for the Arts | Toronto |
| St Luke Learning Centre | Thornhill |
| St Lukes Catholic Parish | Thornhill |
| St Lukes Lodge | Thornhill |
| St Luke's Roman Catholic Church | Thornhill |
| St Marks Apartments | Richmond Hill |
| St Mary Immaculate Roman Catholic Church | Richmond Hill |
| St Mary's Anglican Church | Richmond Hill |
| St Matthews Non-Profit Homes Inc | Richmond Hill |
| St Matthews United Church | Richmond Hill |
| St Panteleimon Greek Orthodox Church of Markham | Markham |
| St Pascal Baylon Church | Thornhill |
| St Patrick Catholic Church (in Schomberg), St Mary Roman Catholic Mission Church (in Nobleton) | King Township |
| St Patrick's Parish | Markham |
| St Pauls Lutheran Church | Richmond Hill |
| St Paul's Lutheran Church, Community Garden | Richmond Hill |
| St Paul's Presbyterian Church | Nobleton |
| St Peters Child Care Centre | Woodbridge |
| St Philip's On-The-Hill Anglican Church | Markham |
| St Thomas the Apostle Roman Catholic Church | Markham |
| St Volodymyr the Great Ukrainian Catholic Church | Markham |
| St. Andrew's College | Aurora |
| St. Andrew's College Archives | Aurora |
| St. Andrews Presbyterian Church | King City |
| St. Jerome YMCA Child Care | Aurora |
| St. John's Rehab Hospital | North York |
| St. Marks Catholic Church | Stouffville |
| St. Paul's Anglican Church | Newmarket |
| Starlight Children's Foundation of Canada. Ontario Chapter | Markham |
| Stars United Baton Club | Richmond Hill |
| Station Creek | Gormley |
| | Statistics Canada | Ottawa |
| Status of Women Canada | Ottawa |
| Step by Step Day Support Services | Richmond Hill |
| Stephen Lewis Foundation, The | Toronto |
| Steppin' Out Theatrical Productions | Richmond Hill |
| STEPS, Society for Permanent Recovery | Richmond Hill |
| | Steward of the Earth | York Region |
| Stock Transportation | Whitchurch-Stouffville |
| Stock Transportation Ltd. | Richmond Hill |
| | Storm Volleyball | Aurora |
| Stouffville Adult Badminton Club | Stouffville |
| Stouffville Amateur Hockey League Mens Division, Women Division (The) | Stouffville |
| Stouffville Business Improvement Area | Stouffville |
| Stouffville Country Market | Stouffville |
| Stouffville Horticultural Society | Stouffville |
| Stouffville Lawn Bowling Club | Stouffville |
| Stouffville Lions | Stouffville |
| | Stouffville Lions Club | Stouffville |
| Stouffville Memorial Christian Church | Stouffville |
| | Stouffville Online | Stouffville |
| Stouffville Pentecostal Church | Stouffville |
| Stouffville Skating Club | Stouffville |
| Stouffville Spirit Hockey Club (The) | Stouffville |
| Stouffville Studio Tour | Stouffville |
| Stouffville United Church | Stouffville |
| Stratford Festival | Stratford |
| | Strawberry Festival (The) | Stouffville |
| Street Outreach Van, LOFT/Crosslinks Street Outreach and Services Network | York Region |
| Stylist On Call, Hairdresser | North York |
| Suburbanaires | Markham |
| Sugarbush Maple Syrup Festival, Toronto and Region Conservation Authority | Toronto |
| Summerski Water Ski Club | King City |
| Summit Community Church | Richmond Hill |
| Summit Golf & Country Club, (The) | Richmond Hill |
| Summit Motel | Richmond Hill |
| Sunnybrook | Toronto |
| Sunnybrook, Geriatric Clinic for Seniors | Toronto |
| Sunrise Assisted Living of Unionville | Markham |
| Sunrise of Aurora | Aurora |
| Sunrise Senior Living - Richmond Hill | Richmond Hill |
| Sunshine Centres for Seniors, Camp Sunshine on Ward's Island | Toronto |
| Swan Lake Village | Markham |
| | Sweet Adelines, North Metro Chapter | Ajax |
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